Photonics takes a new look at bioprocesses.

Laser Focus World, March 2008
Authored by Mark Selker and Barb Paldus.
 
Optically based monitoring of bioprocess reactors enables real-time, noninvasive interrogation of the bioprocess state, bringing the promise of significant improvements in process reproducibility and yield.
 
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Future Pharmaceuticals Magazine Q1 2008

Tapestry of Individuals Offers Unique Solutions

Finesse Solutions LLC was founded in the summer of 2005 with the intent of creating novel optical sensors. As the company evolved we identified the life science applications, particularly in biotechnology, as an interesting starting point...

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Bioprocess Advances Aim to Streamline Operations
Single-Use Components Take Center Stage at Interphex 2008

Genetic Engineering & Biotechnology News
May 1 2008 (Vol. 28, No. 9)

Thousands of professionals from the pharmaceutical and biopharmaceutical industries gathered at “Interphex” in Philadelphia on March 26–28. Educational presentations, workshops, and the opportunity for companies to display and demonstrate their latest products...

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Single Use Systems: Optical Sensors and Bioreactors
The Single-Use Revolution

BTi Magazine
September, 2008

New optical sensors have recently begun to gain popularity in the single-use arena as they can offer relief from many of the challenges that come with using traditional probes, while simultaneously meeting the required criteria...

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Disposable Use Proliferates in Production

Genetic Engineering and Biotechnology News
Sep 15 2008 (Vol. 28, No. 16)

Converts Insist that Single-Use Systems Are Surefire Way to Save Time and Money
Disposable bioprocess equipment has achieved a level of acceptance that was largely unanticipated a decade ago. Single-use bags, tubing, connectors, and related products have profited from rising protein titers that have caused many processes to shrink in size. Disposables have become particularly attractive among contract manufacturers operating at up to the 500 L scale...

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Single-Use Optical Sensors: Ushering in a New Era of PAT for Bio-Processing

CHEManager Europe
December 2008

Catching-Up
Despite the rapid adoption of the process analytical technology (PAT) initiative by the petrochemical and pharmaceutical industries, the implementation of PAT in biotechnology has been slow, primarily owing to the complexity of large molecular products and the living organisms that produce them. The benefits of embracing PAT in bioprocessing are significant, because understanding the bioprocess and optimizing production efficiency directly result in improving the product and yield...

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Life Science Leader
March 2009

Buoyed by the inherent diminution of cleaning requirements and more favorable cost and technical considerations, the adoption of single-use or disposable bioprocessing components is on a growth trajectory.... read the article

Innovations in Pharmaceutical Technology
March 2009

Single-Use Solutions for Scale-Up and Technology Transfer
The development of systems specifically for use with single-use bioreactors will help facilitate scale-up and enable both inter- and intra-company process transfers.

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Next Generation Pharmaceutical
June 2009

Single-use Sensors for Upstream Applications
One of the largest factors limiting the proliferation of single-use bioreactors in cGMP and production environments is the lack of reliable and well engineered single-use sensors. Although the same process parameters are measured in both stainless steel and single-use reactors, the details of the calibration, sterilization, and introduction of the sensors into the bioreactor are substantively different.

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      NGP e-magazine

Future Pharma Single-Use Sensors Executive Podcast
February 2010

Sensor Switch - How disposables could change your manufacturing
Electrochemical sensors have dominated the market for years, but experts from Finesse Solutions argue single-use sensors can save pharma and biotech companies both time and money. Barbara Paldus and Mark Selker of Finesse discuss making the switch to disposables.

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