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TruFluor DO

TruFluorDO

Features

■ Sheath, optical reader and transmitter
■ Excellent precision and accuracy
■ Gamma radiation resistant Smartchip for self-calibration and lot traceability
■ USP Class VI, gamma radiation resistant wetted materials
■ Plug-and-play

TruFluor DO
Single Use Optical Dissolved Oxygen Probe

The TruFluor™ dissolved oxygen and temperature sensor is a single-use solution consisting of a disposable sheath, an optical reader, and a transmitter. The single-use sheath can be pre-inserted in a disposable bioreactor bag port and irradiated with the bag, in order to both preserve and guarantee the sterile barrier. All wetted materials of the sheath are USP class VI compliant.

The optical reader utlizes an LED and a large area photodiode with integrated optical filtering, that minimizes photo-degradation of the acting sensing element. The design has been optimized to provide accurate in-situ measurement of dissolved oxygen using phase fluorometric detection in real time. The temperature measurement leverages a 316L stainless steel thermal window embedded in the sheath, and provides a highly accurate temperature measurement that can be used as a process variable or fortemperature compensation.

Environmental Specifications
Parameter Units Min Type Max
Operating
Temperature		 °C 4 45
Pressure Bar (psi) (0 non-
freezing)		 1
(14.7)		 2
(29.4)
Storage Temperature °C 0 22 65
Relative Humidity
(non-condensing)		 % 0 60 100
Altitude feet 40k
Materials USP Class VI and 316L Electro-polished SS
Performance Specifications

Min Max
Sample Rate Sample rate can be set so that samples are taken in increments from 1 second to 30 minutes
Measuring Range O2 ~ 0 52.5% O2 ( 250% air-sat)
Limit of Detection 0.03% O2
Precision 0.55% or < 3% (whichever is greater) of reading at all temperatures and O2 levels < 21% *
Accuracy at 20 °C < ± 1% at 20.95% O2
Response Time (sec) <40 (agitated, 90%) <60 (not agitated, 90%)
Calibration Pre-calibrated (gamma-radiation-resistant chip)
Gamma Radiation Tested to 50 kGy (typical 25 - 40 kGy)
Cross Sensitivity Organic solvents (e.g. toluene, acetone, benzene, methylene chloride) SO2 and Cl2 gas
Temperature Accuracy Precision
From 5 to 45°C ** ± 0.25°C ± 0.1°C
From 15 to 40°C * ± 0.15°C ± 0.1°C

*Statistically significant data taken at ~15% O2 and 37.5°C. All data
extrapolated therein. Reader to reader precision for any sheath.

** With ambient temperature ~ 25°C

TruFluor is a trademark of Finesse Solutions,
LLC. © Finesse Solutions, LLC, 2010.

TruFluor pH

TruFluorpH

Features

■ Sheath, optical reader, and transmitter
■ Minimal long-term drift
■ Gamma radiation resistant Smartchip for
self-calibration and lot traceability
■ USP Class VI, gamma radiation resistant
wetted materials
■ Plug-and-play

TruFluor pH
Single Use Optical pH Probe

The TruFluor™ pH and temperature sensor is a singleuse
solution consisting of a disposable sheath, an
optical reader, and a transmitter. The single-use
sheath can be pre-inserted in a disposable bioreactor
bag port and irradiated with the bag, in order to both
preserve and guarantee the sterile barrier. All wetted
materials of the sheath are USP class VI compliant.

The optical reader utilizes an LED and a large area
photodiode with integrated optical filtering, that
minimizes photo-degradation of the acting sensing
element. The design has been optimized to provide
accurate in-situ measurement of pH using phase
fluorometric detection in real time.

The temperature measurement leverages a 316L
stainless steel thermal window embedded in the
sheath, and provides a highly accurate temperature
measurement that can be used as a process
variable, or for temperature compensation.

Environmental Specifications
Parameter Units Min Typ Max
Operating Temperature °C 4   45
Operating Pressure Bar (psi)   1(14.7) 2(29.4)
Storage Temperature °C 0 22 65
Storage Relative Humidity (non-condensing) % 0 60 100
Altitude feet     40,000
Materials USP Class VI and 316L electro-polishged SS
Performance Specifications

Min Max
Sample Rate Sample rate can be set so that samples are taken in increments from 1 second to 30 minutes
Measuring Range (pH) 5.5 8.5
Specification Range (pH) 5.5 7.5
Relative Accuracy (pH) +/- 0.1 pH units over +/- 0.5 pH range centered at 1-point standardization pH value
Accuracy at 37.5 °C Depends on accuracy of method and off-line analyzer used for 1-point standardization.
Response Time (sec) <90 (agitated, 90%)
Drift < 0.05 pH units over 21 days for a standard process sampling once every 5 seconds
Calibration Pre-calibrated (gamma-radiation-resistant chip). Conventional 2-point cal possible. 1-point standardization required.
Gamma Radiation Tested to 50 kGy (typical 25 - 40 kGy)
Temperature Accuracy Precision
From 4 to 45°C ± 0.25°C ± 0.1°C
From 15 to 40°C ± 0.15°C ± 0.1°C

TruConnect,TruLogic and TruBio are trademarks of Finesse Solutions, LLC. © Finesse Solutions, LLC, 2009.

TruTorr

TruFluorpH

Features

■ Single-use pressure sensor, cable and transmitter
■ Self-calibrated for immediate use
■ Wetted Materials USP Class VI
■ Plug-and-play
■ Gamma radiation resistant to 50 kGy

TruTorr
Single-use Headspace Pressure Sensor

The TruTorr™ pressure sensing system is a single-use solution for measuring headspace pressure in a single-use container in order to prevent damage from overpressure. The product consists of a disposable pressure sensor, a cable, and a transmitter that is seamlessly integrated into Finesse TruViu™ hardware (RDPD, PLSSmini or PLSS). The single-use sensor not only compensates for temperature, but is self-calibrated for immediate use, based on integrated, gammaradiation- resistant memory chip technology. Simply attach the cable to the sensor, and set your TruBio® DV control system alarm levels or interlocks for bag overpressure, and start your process.

The single-use sensor can be pre-inserted in a disposable bioreactor bag port and irradiated with the bag, in order to both preserve and guarantee the sterile barrier. All wetted materials of the sensor are USP class VI compliant. Each sensor’s certificate of compliance can be downloaded from the Finesse web site.

Environmental Specifications
Parameter Units Min Typ Max
Operating Temperature °C 15   45
Operating Pressure Psi (bar)   14.7
(1)		  
Storage Temperature °C 0 22 65
Storage Relative Humidity (non-condensing) % 10 60 90
Altitude ft
(m)		     10000
(3048)
Shock tolerance (non-operating) ship-
ping		 JIS Z
0202:
1994		    
Performance Specifications

Min Max
Measuring Range
(pressure gauge)		 0 psi
0 bar		 7 psi
0.48 bar
Drift 0.2 psig (0.0014 bar gauge) over 21 days
Limit of Detection (psi) 0.01
Relative Accuracy (pH) +/- 0.1 pH units over +/- 0.5 pH range centered at 1-point standardization pH value
Accuracy at 20 °C Accuracy (at 25°C): ±0.2 psig (±0.0014 bar gauge)
or ±2% of the reading, whichever is greater
(including drift 21 days)
Response Time (sec) ≤ 2
90% response (sec) < 1
Calibration

Pre-calibrated

1 point standardization optional through TruBio software
Cross Sensitivity None
Temperature Automatic compensation over operating range

 

 

TruTorr, TruViu and TruBio are trademarks of Finesse Solutions, LLC. © Finesse Solutions, LLC, 2010.

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